inversely, modulate claudin oligomerization
نویسندگان
چکیده
Jimmi Cording, Johanna Berg, Nadja Käding, Christian Bellmann, Christian Tscheik, Julie K. Westphal, Susanne Milatz, Dorothee Günzel, Hartwig Wolburg, Jörg Piontek, Otmar Huber and Ingolf Ernst Blasig* Leibniz-Institut für Molekulare Pharmakologie, Robert-Rössle-Str. 10, 13125 Berlin, Germany Institute of Biochemistry II, Jena University Hospital, Nonnenplan 2, 07743 Jena, Germany Institut für Klinische Physiologie CBF, Charité, Freie Universität und Humboldt-Universität, Berlin Institute of Pathology and Neuropathology, Department of General Pathology, University of Tübingen, Medical School Tübingen, 72076 Germany
منابع مشابه
In tight junctions, claudins regulate the interactions between occludin, tricellulin and marvelD3, which, inversely, modulate claudin oligomerization.
Tight junctions seal the paracellular cleft of epithelia and endothelia, form vital barriers between tissue compartments and consist of tight-junction-associated marvel proteins (TAMPs) and claudins. The function of TAMPs and the interaction with claudins are not understood. We therefore investigated the binding between the TAMPs occludin, tricellulin, and marvelD3 and their interaction with cl...
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تاریخ انتشار 2013